Patnaik, Pratap R (2009) Transient response analysis of the eukaryotic chemosensory system to intra-cellular fluctuations. Journal of bioinformatics and computational biology, 7 (1). pp. 93-105. ISSN 0219-7200
Full text not available from this repository. (Request a copy)Abstract
Like prokaryotic cells, those of eukaryotes are also subjected to noise from within the cells. While the cells have a built-in mechanism to attenuate the noise, conditions may arise where this is beyond the cell's ability to regulate. Start-up perturbations and those induced by metabolic shifts are examples of such situations. Then, it becomes useful to understand how the cells respond. For a eukaryotic chemosensory system, this has been studied by applying response coefficient analysis to a recent model. With even three dependent variables - an activator, an inhibitor, and a response element - the response coefficients differ widely with time and from one variable to another. These differences are interpreted in terms of the chemosensory mechanism and its robustness. The results complement similar recent studies of Escherichia coli chemotaxis, thus supporting their credibility and versatility.
| Item Type: | Article |
|---|---|
| Additional Information: | Copyright of this article belongs to World Scientific Publishing. |
| Uncontrolled Keywords: | Eukaryotic cells; chemosensory system; intra-cellular noise; transient response |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 28 Feb 2012 16:10 |
| Last Modified: | 28 Feb 2012 16:10 |
| URI: | http://crdd.osdd.net/open/id/eprint/1096 |
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