Bio-functionalized graphene-graphene oxide nanocomposite based electrochemical immunosensing.

Sharma, Priyanka and Tuteja, Satish K and Bhalla, Vijayender and Shekhawat, G and Dravid, Vinayak P and Suri, C Raman (2013) Bio-functionalized graphene-graphene oxide nanocomposite based electrochemical immunosensing. Biosensors & bioelectronics, 39 (1). pp. 99-105. ISSN 1873-4235

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Abstract

We report a novel in-situ electrochemical synthesis approach for the formation of functionalized graphene-graphene oxide (fG-GO) nanocomposite on screen-printed electrodes (SPE). Electrochemically controlled nanocomposite film formation was studied by transmission electron microscopy (TEM) and Raman spectroscopy. Further insight into the nanocomposite has been accomplished by the Fourier transformed infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA) and X-ray diffraction (XRD) spectroscopy. Configured as a highly responsive screen-printed immunosensor, the fG-GO nanocomposite on SPE exhibits electrical and chemical synergies of the nano-hybrid functional construct by combining good electronic properties of functionalized graphene (fG) and the facile chemical functionality of graphene oxide (GO) for compatible bio-interface development using specific anti-diuron antibody. The enhanced electrical properties of nanocomposite biofilm demonstrated a significant increase in electrochemical signal response in a competitive inhibition immunoassay format for diuron detection, promising its potential applicability for ultra-sensitive detection of range of target analytes.

Item Type:	Article
Additional Information:	Copyright of this article belongs to Elsevier Science.
Uncontrolled Keywords:	Functionalised graphene–graphene oxide;Nanocomposites; Specific antibodies; Diuron;Electrochemical immunosensor
Subjects:	Q Science > QR Microbiology
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	31 Jan 2013 04:05
Last Modified:	31 Jan 2013 04:05
URI:	http://crdd.osdd.net/open/id/eprint/1223

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