Functional characterization of a novel outer membrane porin KpnO, regulated by PhoBR two-component system in Klebsiella pneumoniae NTUH-K2044.

Srinivasan, Vijaya Bharathi and Venkataramaiah, Manjunath and Mondal, Amitabha and Vaidyanathan, Vasanth and Govil, Tanvi and Rajamohan, Govindan (2012) Functional characterization of a novel outer membrane porin KpnO, regulated by PhoBR two-component system in Klebsiella pneumoniae NTUH-K2044. PloS one, 7 (7). e41505. ISSN 1932-6203

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Abstract

The diffusion of antibiotics through the outer membrane is primarily affected by the porin super family, changes contribute to antibiotic resistance. Recently we demonstrated that the CpxAR two-component signaling system alters the expression of an uncharacterized porin OmpC(KP), to mediate antimicrobial resistance in K. pneumoniae.

Item Type: Article
Additional Information: OPEN ACCESS
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 30 Jan 2013 06:33
Last Modified: 30 Jan 2013 06:33
URI: http://crdd.osdd.net/open/id/eprint/1226

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