Stem bromelain-induced macrophage apoptosis and activation curtail Mycobacterium tuberculosis persistence.

Mahajan, Sahil and Chandra, Vemika and Dave, Sandeep and Nanduri, Ravikanth and Gupta, Pawan (2012) Stem bromelain-induced macrophage apoptosis and activation curtail Mycobacterium tuberculosis persistence. The Journal of infectious diseases, 206 (3). pp. 366-76. ISSN 1537-6613

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Official URL: http://jid.oxfordjournals.org/content/206/3/366.fu...

Abstract

Mycobacterium tuberculosis, the causative agent of tuberculosis, has a remarkable ability to usurp its host's innate immune response, killing millions of infected people annually. One approach to manage infection is prevention through the use of natural agents. In this regard, stem bromelain (SBM), a pharmacologically active member of the sulfhydryl proteolytic enzyme family, obtained from Ananas comosus and possessing a remarkable ability to induce the innate and acquired immune systems, is important.

Item Type: Article
Additional Information: Copyright of this article belongs to OUP.
Subjects: R Medicine > R Medicine (General)
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 28 Jan 2013 11:19
Last Modified: 28 Jan 2013 11:19
URI: http://crdd.osdd.net/open/id/eprint/1248

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