Srinivasan, Vijaya Bharathi and Vaidyanathan, Vasanth and Mondal, Amitabha and Rajamohan, Govindan (2012) Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044. PloS one, 7 (4). e33777. ISSN 1932-6203
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Abstract
Klebsiella pneumoniae is a gram-negative, non-motile, facultative anaerobe belonging to the Enterobacteriaceae family of the γ-Proteobacteria class in the phylum Proteobacteria. Multidrug resistant K. pneumoniae have caused major therapeutic problems worldwide due to emergence of extended-spectrum β-lactamase producing strains. Two-component systems serve as a basic stimulus-response coupling mechanism to allow organisms to sense and respond to changes in many different environmental conditions including antibiotic stress.
| Item Type: | Article |
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| Additional Information: | OPEN ACCESS |
| Uncontrolled Keywords: | Anti-Bacterial Agents; Microbial Sensitivity Tests; Oxidative Stress |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 28 Jan 2013 07:16 |
| Last Modified: | 28 Jan 2013 07:16 |
| URI: | http://crdd.osdd.net/open/id/eprint/1254 |
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