Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv).

Singla, Deepak and Tewari, Rupinder and Kumar, Ashwani and Raghava, G.P.S. (2013) Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv). Chemistry Central journal, 7 (1). p. 49. ISSN 1752-153X

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Abstract

Mycobacterium tuberculosis (M.tb) is the causative agent of tuberculosis, killing ~1.7 million people annually. The remarkable capacity of this pathogen to escape the host immune system for decades and then to cause active tuberculosis disease, makes M.tb a successful pathogen. Currently available anti-mycobacterial therapy has poor compliance due to requirement of prolonged treatment resulting in accelerated emergence of drug resistant strains. Hence, there is an urgent need to identify new chemical entities with novel mechanism of action and potent activity against the drug resistant strains.

Item Type:	Article
Additional Information:	OPEN ACCESS
Subjects:	Q Science > QR Microbiology
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	24 Jun 2013 11:00
Last Modified:	24 Jun 2013 11:00
URI:	http://crdd.osdd.net/open/id/eprint/1304

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