Tuteja, Satish K and Sabherwal, Priyanka and Deep, Akash and Rastogi, Richa and Paul, Ashok K and Suri, C Raman (2014) Biofunctionalized rebar graphene (f-RG) for label-free detection of cardiac marker troponin I. ACS applied materials & interfaces, 6 (17). pp. 14767-71. ISSN 1944-8252
Full text not available from this repository. (Request a copy)Abstract
One-step microwave-assisted unscrolling of carbon nanotubes to form functionalized rebar graphene (f-RG) is reported. The well-characterized f-RG on an interdigitated electrode biochip in a FET configuration showed enhanced electronic properties, as demonstrated with I-V characteristics. The developed device was biofunctionalized with specific anti-cTnI antibodies exhibiting a shift of threshold voltage from -2.15 V to -0.5 V and decrease in electron mobility from 3.609 × 10(4) to 8.877 × 10(3) cm(2) V(-1) s(-1). The new sensing strategy holds great promise for its applicability in diagnostics exhibiting high sensitivity (∼ 1 pg/mL) and specificity toward cardiac marker (cTnI).
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | biochip; carbon nanotubes; cardiac marker; clinical diagnostics; functionalized rebar graphene; troponin I |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 09 Feb 2015 04:56 |
| Last Modified: | 09 Feb 2015 04:56 |
| URI: | http://crdd.osdd.net/open/id/eprint/1536 |
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