Novel immunosuppressive agent caerulomycin A exerts its effect by depleting cellular iron content.

Kaur, Suneet and Srivastava, Gautam and Sharma, Amar Nath and Jolly, R S (2015) Novel immunosuppressive agent caerulomycin A exerts its effect by depleting cellular iron content. British journal of pharmacology, 172 (9). pp. 2286-99. ISSN 1476-5381

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Abstract

Recently, we have described the use of caerulomycin A (CaeA) as a potent novel immunosuppressive agent. Immunosuppressive drugs are crucial for long-term graft survival following organ transplantation and treatment of autoimmune diseases, inflammatory disorders, hypersensitivity to allergens, etc. The objective of this study was to identify cellular targets of CaeA and decipher its mechanism of action.

Item Type: Article
Additional Information: Copyright of this article belongs to John & wile
Uncontrolled Keywords: caerulomycin, Pharmacology
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 10 Jul 2015 03:49
Last Modified: 22 Jul 2015 04:09
URI: http://crdd.osdd.net/open/id/eprint/1668

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