Prediction and classification of ncRNAs using structural information.

Panwar, Bharat and Arora, Amit and Raghava, G.P.S. (2014) Prediction and classification of ncRNAs using structural information. BMC genomics, 15. p. 127. ISSN 1471-2164

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Official URL: http://www.biomedcentral.com/1471-2164/15/127

Abstract

Evidence is accumulating that non-coding transcripts, previously thought to be functionally inert, play important roles in various cellular activities. High throughput techniques like next generation sequencing have resulted in the generation of vast amounts of sequence data. It is therefore desirable, not only to discriminate coding and non-coding transcripts, but also to assign the noncoding RNA (ncRNA) transcripts into respective classes (families). Although there are several algorithms available for this task, their classification performance remains a major concern. Acknowledging the crucial role that non-coding transcripts play in cellular processes, it is required to develop algorithms that are able to precisely classify ncRNA transcripts.

Item Type: Article
Additional Information: Open Access
Uncontrolled Keywords: ncRNA; SVM; RandomForest; Graph properties; Prediction; RNAcon
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 20 Jul 2015 03:41
Last Modified: 20 Jul 2015 03:41
URI: http://crdd.osdd.net/open/id/eprint/1711

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