A highly efficient designer cell for enantioselective reduction of ketones

Srivastava, Gautam and Pal, Mohan and Kaur, Suneet and Jolly, R S (2015) A highly efficient designer cell for enantioselective reduction of ketones. Catalysis Science & Technology, 5 (1). pp. 105-108. ISSN 2044-4753

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Official URL: http://dx.doi.org/10.1039/C4CY01017E

Abstract

A designer cell, surf-crs-gdh, coexpressing carbonyl reductase (crs) and glucose dehydrogenase (gdh) on the cell surface has been constructed and its enzyme activities are compared with those of the corresponding cell, cyto-crs-gdh, coexpressing crs and gdh in cytosol. For various ketones, surf-crs-gdh exhibited 48- to 265-fold higher crs activity per unit protein compared to cyto-crs-gdh.

Item Type: Article
Additional Information: Copyright of this article belongs to RSC.
Uncontrolled Keywords: Ketones
Subjects: Q Science > QD Chemistry
Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 29 Jan 2016 07:53
Last Modified: 01 Feb 2016 11:35
URI: http://crdd.osdd.net/open/id/eprint/1781

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