Chopra, Lipsy and Singh, Gurdeep and Jena, Kautilya Kumar and Verma, Himanshu and Sahoo, Debendra K (2015) Bioprocess development for the production of sonorensin by Bacillus sonorensis MT93 and its application as a food preservative. Bioresource Technology, 175. pp. 358-366. ISSN 09608524
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Media composition and environmental conditions were optimized using statistical tools, Plackett Burman design and response surface methodology, to maximize the yield of a bacteriocin, named as sonorensin, from a new marine isolate Bacillus sonorensis MT93 showing broad spectrum of antimicrobial activity. Under optimized conditions, MT93 produced 15-fold higher yield of sonorensin compared to that under initial fermentation conditions. As oxygen supply is a critical parameter controlling growth and product formation in aerobic bioprocesses and used as a parameter for bioprocess scale up, the effects of oxygen transfer, in terms of volumetric oxygen transfer coefficient (kLa), on production of sonorensin was investigated using optimized medium composition in a bioreactor. Studies on effectiveness of sonorensin against Staphylococcus aureus and Listeria monocytogenes in fruit juice and as a preservative in pasteurized milk demonstrated its potential as a biopreservative in fruit products and shelf life extender of the pasteurized milk.
| Item Type: | Article |
|---|---|
| Additional Information: | Copyright of this article belongs to Elsevier Science |
| Uncontrolled Keywords: | Bacillus sonorensis; Sonorensin; Optimization; Volumetric oxygen transfer coefficient; Biopreservative |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 01 Feb 2016 13:13 |
| Last Modified: | 01 Feb 2016 13:13 |
| URI: | http://crdd.osdd.net/open/id/eprint/1815 |
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