Prediction of anticancer molecules using hybrid model developed on molecules screened against NCI-60 cancer cell lines.

Singh, Harinder and Kumar, Rahul and Singh, Sandeep and Chaudhary, Kumardeep and Gautam, Ankur and Raghava, G.P.S. (2015) Prediction of anticancer molecules using hybrid model developed on molecules screened against NCI-60 cancer cell lines. BMC cancer, 16 (1). p. 77. ISSN 1471-2407

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Abstract

In past, numerous quantitative structure-activity relationship (QSAR) based models have been developed for predicting anticancer activity for a specific class of molecules against different cancer drug targets. In contrast, limited attempt have been made to predict the anticancer activity of a diverse class of chemicals against a wide variety of cancer cell lines. In this study, we described a hybrid method developed on thousands of anticancer and non-anticancer molecules tested against National Cancer Institute (NCI) 60 cancer cell lines.

Item Type:	Article
Additional Information:	Open Access
Uncontrolled Keywords:	Bioinformatics, cancer
Subjects:	Q Science > QR Microbiology
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	29 Sep 2016 06:17
Last Modified:	29 Sep 2016 06:17
URI:	http://crdd.osdd.net/open/id/eprint/1833

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