Conceptualizing "suicidal genetically engineered microorganisms" for bioremediation applications.

Pandey, Gunjan and Paul, Debarati and Jain, R K (2005) Conceptualizing "suicidal genetically engineered microorganisms" for bioremediation applications. Biochemical and biophysical research communications, 327 (3). pp. 637-9. ISSN 0006-291X

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Abstract

Use of genetically modified microorganisms (GEMs) for pollution abatement has been limited because of risks associated with their release in the environment. Recent developments in the area of recombinant DNA technologies have paved the way for conceptualizing "suicidal genetically engineered microorganisms" (S-GEMS) to minimize such anticipated hazards and to achieve efficient and safer bioremediation of contaminated sites. Our strategy of designing a novel S-GEM is based on the knowledge of killer-anti-killer gene(s) that would be susceptible to programmed cell death after detoxification of any given contaminated site(s).

Item Type:	Article
Additional Information:	Copyright of this article belongs to Elsevier Science.
Uncontrolled Keywords:	Environment pollution; Bioremediation; Plasmid addiction systems; Suicidal genetically modified microorganisms
Subjects:	Q Science > QD Chemistry
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	08 Jan 2012 05:43
Last Modified:	03 Apr 2012 07:24
URI:	http://crdd.osdd.net/open/id/eprint/192

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