Shukla, Deepak and Mondal, Amitabha and Venkataramaiah, Manjunath and Rajamohan, Govindan and Srinivasan, Vijaya Bharathi (2016) Occurrence of Diverse Antimicrobial Resistance Determinants in Genetically Unrelated Biocide Tolerant Klebsiella pneumoniae. PLOS ONE, 11 (11). e0166730. ISSN 1932-6203
Full text not available from this repository. (Request a copy)Abstract
Nosocomial infections due to Klebsiella pneumoniae is a significant problem in health care settings worldwide. In this study, we examined the antimicrobial susceptibility, genetic profiles and mechanisms of antibiotic resistance in K. pneumoniae isolates of Indian origin. To our knowledge this is the first report demonstrating the high prevalence of β-lactamases, aminoglycoside modifying enzymes, quinolone resistance genes besides demonstrating the involvement of active efflux in K. pneumoniae Indian isolates. This study has enabled us to correlate the phenotypic and genotypic characteristics in K. pneumoniae, providing an important base for continued monitoring and epidemiological studies of this emerging nosocomial pathogen in Indian hospitals.
| Item Type: | Article |
|---|---|
| Additional Information: | Open Access |
| Uncontrolled Keywords: | Aminoglycosides/metabolism Anti-Bacterial Agents/pharmacology* Cross Infection Drug Resistance, Bacterial* |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 24 Mar 2018 04:04 |
| Last Modified: | 24 Mar 2018 04:04 |
| URI: | http://crdd.osdd.net/open/id/eprint/1978 |
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