Muthu Krishnan, S. (2018) Using Chou's general PseAAC to analyze the evolutionary relationship of receptor associated proteins (RAP) with various folding patterns of protein domains. Journal of Theoretical Biology, 445. pp. 62-74. ISSN 00225193
Full text not available from this repository. (Request a copy)Abstract
The receptor-associated protein (RAP) is an inhibitor of endocytic receptors that belong to the lipoprotein receptor gene family. In this study, a computational approach was tried to find the evolutionarily related fold of the RAP proteins. Through the structural and sequence-based analysis, found various protein folds that are very close to the RAP folds. Remote homolog datasets were used potentially to develop a different support vector machine (SVM) methods to recognize the homologous RAP fold. This study helps in understanding the relationship of RAP homologs folds based on the structure, function and evolutionary history.
| Item Type: | Article |
|---|---|
| Additional Information: | Copyright of this article belongs to Elsevier Science. |
| Uncontrolled Keywords: | Molecular evolution; PSSM; Rap protein fold; Support vector machine |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 27 Mar 2018 05:09 |
| Last Modified: | 20 Mar 2019 12:46 |
| URI: | http://crdd.osdd.net/open/id/eprint/2018 |
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