Lactic acid bacteria isolated from yak milk show probiotic potential

Kaur, Manpreet and Singh, Harjodh and Jangra, Manoj and Kaur, Lakhwinder and Jaswal, Pallavi and Dureja, Chetna and Nandanwar, Hemraj and Chaudhuri, Saumya Ray and Raje, Manoj and Mishra, Sunita and Pinnaka, Anil Kumar (2017) Lactic acid bacteria isolated from yak milk show probiotic potential. Applied Microbiology and Biotechnology, 101 (20). pp. 7635-7652. ISSN 0175-7598

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Probiotic industries strive for new, efficient and promising probiotic strains that impart a positive impact on consumer health. Challenges are persisting in isolation, screening, and selection of the new indigenous probiotic strains. In the present research, we explored the probiotic potential of 17 lactic acid bacteria isolated from Yak milk in a series of in vitro tests. We also demonstrated their health benefits, i.e., cholesterol degradation, lactose digestion, antimicrobial activity, antioxidant, and anticancer activities. Principal component analysis revealed that more than 50% of the strains fulfilled the examined criteria, e.g., survival in acidic pH, bile concentrations, and adherent property. Approximately all the strains produced antimicrobial substances against the maximum number of tested strains including clinical strains. Most strains degraded cholesterol in comparison to the reference probiotic strain whereas strain Yc showed 1.5 times higher the degradation efficiency of the control strain. Lan4 strain exhibited remarkable anticancer activity and induced the maximum apoptosis (87%) in the Hela cells and was non-toxic to the non-cancerous HEK293 cells. Around ten strains showed positive lactose digestion. Overall, this can be concluded that selected lactic acid bacteria revealed excellent probiotic properties along with desirable health benefits. These strains need to be further investigated in details for their application in the development of novel probiotic preparations for the improvement of public health.

Item Type: Article
Additional Information: Copyright of this article belongs to Springer.
Uncontrolled Keywords: Cholesterol degradation; Lactic acid bacteria; Probiotics; Yak milk
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 28 Mar 2018 03:18
Last Modified: 28 Mar 2018 03:18

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