rocess for the isolation of a nontoxinogenic vibrio cholerae strain and a process for preparing cholera vaccine from said vibrio cholerae strain

Muthukumarappa, Thungapathra and Ghosh, Amit and Sharma, Charu and Gupta, Naveen and Mukhopadhyay, Ashish and Hemanta, Kole and Nair, Gopinath and Ghosh, Balakrish and Kumar, Ranajit (2000) rocess for the isolation of a nontoxinogenic vibrio cholerae strain and a process for preparing cholera vaccine from said vibrio cholerae strain.

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Abstract

A process for the isolation of nontoxinogenic V. cholerae strain and a process for preparing a cholera vaccine from said V. cholerae strain, said process comprising (a) isolating V. cholerae from the stool of a patient suffering from cholera by spreading the stool on a selector medium specific for V. cholerae, (b) separating the non-toxinogenic V. cholerae strain from the population of the V. cholerae strains isolated in step (a), and (c) incorporating immunogenic cholera toxin (ctx) B subunit gene into the chromosome of the strain by conventional methods to produce the vaccine.

Item Type: Article
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 26 Jul 2018 06:01
Last Modified: 15 Nov 2019 10:05
URI: http://crdd.osdd.net/open/id/eprint/2091

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