A genomic analysis of Mycobacterium immunogenum strain CD11_6 and its potential role in the activation of T cells against Mycobacterium tuberculosis.

Kaur, Gurpreet and Chander, Atul Munish and Kaur, Gurwinder and Maurya, Sudeep Kumar and Nadeem, Sajid and Kochhar, Rakesh and Bhadada, Sanjay Kumar and Agrewala, J N and Mayilraj, Shanmugam (2019) A genomic analysis of Mycobacterium immunogenum strain CD11_6 and its potential role in the activation of T cells against Mycobacterium tuberculosis. BMC microbiology, 19 (1). p. 64. ISSN 1471-2180

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Abstract

Mycobacterium tuberculosis (Mtb) is an etiological agent of tuberculosis (TB). Tuberculosis is a mounting problem worldwide. The only available vaccine BCG protects the childhood but not adulthood form of TB. Therefore, efforts are made continuously to improve the efficacy of BCG by supplementing it with other therapies. Consequently, we explored the possibility of employing Mycobacterium immunogenum (Mi) to improve BCG potential to protect against Mtb.

Item Type: Article
Additional Information: Open Access
Uncontrolled Keywords: Immune response; Mycobacterium bovis (Mb); Mycobacterium immunogenum (Mi); Mycobacterium tuberculosis (Mtb); T cell memory; Whole genome sequencing
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 13 Aug 2019 12:10
Last Modified: 13 Aug 2019 12:10
URI: http://crdd.osdd.net/open/id/eprint/2357

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