Ahmed, Firoz and Kaundal, Rakesh and Raghava, g (2013) PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors. BMC bioinformatics, 14 Sup. S9. ISSN 1471-2105
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Abstract
Dicer, an RNase III enzyme, plays a vital role in the processing of pre-miRNAs for generating the miRNAs. The structural and sequence features on pre-miRNA which can facilitate position and efficiency of cleavage are not well known. A precise cleavage by Dicer is crucial because an inaccurate processing can produce miRNA with different seed regions which can alter the repertoire of target genes.
| Item Type: | Article |
|---|---|
| Additional Information: | Open Access |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 05 Sep 2019 14:04 |
| Last Modified: | 05 Sep 2019 14:04 |
| URI: | http://crdd.osdd.net/open/id/eprint/2429 |
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