Immunosensors for pesticide analysis: antibody production and sensor development.

Suri, C Raman and Raje, Manoj and Varshney, Grish C (2002) Immunosensors for pesticide analysis: antibody production and sensor development. Critical reviews in biotechnology, 22 (1). pp. 15-32. ISSN 0738-8551

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Abstract

Immunosensors, a type of affinity biosensor, are based on the binding interactions between an immobilized biomolecule (antibody/antigen) on the electronic transducer surface with the analyte of interest (antigen/antibody), resulting in a detectable signal. The sensor system takes advantage of the high selectivity provided by the molecular recognition characteristic of an antibody, which binds reversibly with a specific antigen. This review article presents the current status of immunosensors, highlighting their potential benefits and limitations for pesticide analysis. The basic criteria for generating specific antibodies against low-molecular-mass pesticides, which are usually nonimmunogenic in nature, are briefly discussed. The article also describes the fundamentals of important transducer technologies and their use in immunosensor development.

Item Type:	Article
Additional Information:	Copyright of this article belongs to Informa Healthcare.
Uncontrolled Keywords:	immunosensor, antibody, immune-complex, pesticides.
Subjects:	Q Science > QR Microbiology
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	05 Jan 2012 15:14
Last Modified:	22 Jul 2015 05:35
URI:	http://crdd.osdd.net/open/id/eprint/271

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