Sen, Himanshu and Kaur, Manpreet and Chaudhuri, Saumya Ray (2024) L-Ascorbic Acid Restricts Vibrio cholerae Survival in Various Growth Conditions. MICROORGANISMS, 12 (3).
Full text not available from this repository. (Request a copy)Abstract
Cholera, a deadly diarrheal disease, continues to ravage various parts of the world. It is caused by Vibrio cholerae, an important member of the gamma-proteobacteria. Based on certain genetic and phenotypic tests, the organism is classified into two major biotypes, namely classical and El Tor. The El Tor and its variants are majorly responsible for the ongoing seventh pandemic across the globe. Previously, we have shown that cross-feeding of glucose metabolic acidic by-products of gut commensals can severely affect the viability of the biotypes. In this work, we examined the effect of L-ascorbic acid on the survival of Vibrio cholerae strains belonging to both biotypes and different serotypes. We observed that L-ascorbic acid effectively restricts the growth of all strains under various conditions including strains adapted to acid stress. In addition, L-ascorbic acid is also effective in decreasing bile-induced biofilms of Vibrio cholerae.
| Item Type: | Article |
|---|---|
| Additional Information: | The copyright of this article belongs to MDPI |
| Uncontrolled Keywords: | L-ascorbic acid; Vibrio cholerae; acetoin; bile salts; biofilm. |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 24 Jun 2024 02:40 |
| Last Modified: | 24 Jun 2024 02:40 |
| URI: | http://crdd.osdd.net/open/id/eprint/3109 |
Actions (login required)
 |
View Item |
