Sharma, Yogesh and Pawar, Ganesh P. and Chaudhari, Vinod (2022) One-Pot Domino Reaction: Direct Access to Polysubstituted 1,4-Benzothiazine 1,1-Dioxide via Water-Gas Shift Reaction Utilizing DMF/H2O. Journal of Organic Chemistry, 88 (1). pp. 701-710.
Full text not available from this repository. (Request a copy)Abstract
Benzothiazine 1,1-dioxide (BTDO) is a privileged chemical motif, and its metal-free domino access is in high demand. Current BTDO production methods require costly metal catalysts or harsh reaction conditions. A facile domino approach to BTDO via a water-gas shift reaction (WGSR) employing sodium 2-nitrobenzenesulfinates and α-bromo ketones is presented. This strategy is cost-effective and environmentally beneficial. The optimized reaction conditions demonstrated remarkable chemical tolerance to a wide range of electrically and sterically varied substituents on both coupling partners.
| Item Type: | Article |
|---|---|
| Additional Information: | The copyright of this article belongs to ACS Publications |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 15 Jul 2024 04:03 |
| Last Modified: | 15 Jul 2024 04:03 |
| URI: | http://crdd.osdd.net/open/id/eprint/3152 |
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