Palladium-Catalyzed Intramolecular C–H Amination via Oxidative Coupling on Indole Derivatives: Access to 11H-Benzo[4,5]imidazo[1,2-a]indoles

Sharma, Yogesh and Kaur, Simran and Kandhasamy, Hariprasath and Sahoo, Subash Chandra and Chaudhari, Vinod D. (2025) Palladium-Catalyzed Intramolecular C–H Amination via Oxidative Coupling on Indole Derivatives: Access to 11H-Benzo[4,5]imidazo[1,2-a]indoles. Organic Letters, 27 (1). pp. 517-521.

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Abstract

A novel palladium-catalyzed intramolecular C–H amination via oxidative coupling exploiting inactivated N-substituted aryl amines on indoles for the one-pot synthesis of novel 11H-benzo[4,5]imidazo[1,2-a]indole derivatives is reported. The optimized reaction conditions accommodated a wide range of electronic variations on both the indole and the pendant aryl amine ring, resulting in products with good to excellent yields.

Item Type: Article
Additional Information: PMID: 39739506
Uncontrolled Keywords: Amines Indoles Organic reactions Oxidative coupling Reaction products
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 01 Feb 2026 13:47
Last Modified: 01 Feb 2026 13:47
URI: http://crdd.osdd.net/open/id/eprint/3269

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