Owais, M and Ahmed, I and Krishnakumar, B and Jain, R K and Bachhawat, B K and Gupta, C M (1993) Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis. FEBS letters, 326 (1-3). pp. 56-8. ISSN 0014-5793
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Abstract
Encapsulation of amphotericin B in tuftsin-bearing liposomes greatly increased its efficacy in treatment of human aspergillosis in mice. Also, the drug efficacy was significantly increased by pretreating the animals with drug-free tuftsin-bearing liposomes. These results demonstrate that macrophage activation can considerably enhance the therapeutic efficacy of antifungal drugs, like amphotericin B.
Item Type: | Article |
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Additional Information: | Copyright of this article belongs to Elsevier Science |
Subjects: | Q Science > QR Microbiology |
Depositing User: | Dr. K.P.S.Sengar |
Date Deposited: | 12 Dec 2011 15:37 |
Last Modified: | 12 Dec 2011 15:37 |
URI: | http://crdd.osdd.net/open/id/eprint/417 |
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