Owais, M and Ahmed, I and Krishnakumar, B and Jain, R K and Bachhawat, B K and Gupta, C M (1993) Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis. FEBS letters, 326 (1-3). pp. 56-8. ISSN 0014-5793

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Abstract

Encapsulation of amphotericin B in tuftsin-bearing liposomes greatly increased its efficacy in treatment of human aspergillosis in mice. Also, the drug efficacy was significantly increased by pretreating the animals with drug-free tuftsin-bearing liposomes. These results demonstrate that macrophage activation can considerably enhance the therapeutic efficacy of antifungal drugs, like amphotericin B.

Item Type:	Article
Additional Information:	Copyright of this article belongs to Elsevier Science
Subjects:	Q Science > QR Microbiology
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	12 Dec 2011 15:37
Last Modified:	12 Dec 2011 15:37
URI:	http://crdd.osdd.net/open/id/eprint/417

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