Regulation of alpha- and beta-tubulin mRNAs in rat brain during synaptogenesis.

Bhattacharya, B and Mandal, C and Basu, S and Sarkar, P K (1987) Regulation of alpha- and beta-tubulin mRNAs in rat brain during synaptogenesis. Brain research, 388 (2). pp. 159-62. ISSN 0006-8993

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Abstract

Developmental alterations in alpha- and beta-tubulin mRNA in polysomes from brains of -3 days (fetal) to 30-day-old rats were quantitated by using well-characterized chicken alpha- and beta-tubulin cDNA probes, pT1 and pT2 having 80-90% homology with rat sequences. Northern blot analysis revealed a single major (greater than 95%) 1.8 kb mRNA for both alpha- and beta-tubulin. Quantitation by slot hybridization indicates a virtually coordinate expression of alpha- and beta-tubulin mRNA with a maximal level around day 5 after birth, which represents the mid-phase of synaptogenesis.

Item Type: Article
Additional Information: Copyright of this articl;e belongs to Elsevier Science.
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 10 Jan 2012 15:24
Last Modified: 10 Jan 2012 15:24
URI: http://crdd.osdd.net/open/id/eprint/641

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