A simple analytical solution of a model for probabilistic plasmid loss, and its implications in continuous cultures

Patnaik, P R (1993) A simple analytical solution of a model for probabilistic plasmid loss, and its implications in continuous cultures. Biotechnology Techniques, 7 (5). pp. 357-360. ISSN 0951-208X

PDF Patnaik1993.3.pdf - Published Version Restricted to Registered users only Download (780Kb) | Request a copy

Abstract

An analytical solution is proposed for a mathematical model of a continuous culture of microorganisms in which the probability of loss of plasmids upon cell division depends on the dilution rate. It is shown that at each instant of time there is an optimal dilution rate from a control viewpoint. Two such time-optimal profiles are derived and compared to determine the effect of wild type cells present initially in the broth.

Item Type:	Article
Additional Information:	Copyright of this article belongs to Springer Science.
Subjects:	Q Science > QR Microbiology
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	16 Jan 2012 15:24
Last Modified:	28 Mar 2014 11:04
URI:	http://crdd.osdd.net/open/id/eprint/677

Actions (login required)

View Item