Cloning and characterization of aspartate-beta-semialdehyde dehydrogenase from Mycobacterium tuberculosis H37 Rv.

Shafiani, S and Sharma, P and Vohra, R M and Tewari, Rupinder (2005) Cloning and characterization of aspartate-beta-semialdehyde dehydrogenase from Mycobacterium tuberculosis H37 Rv. Journal of applied microbiology, 98 (4). pp. 832-8. ISSN 1364-5072

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Abstract

The ASD enzyme is a validated drug target. We characterized this enzyme from M. tuberculosis and future work would focus on deducing the three-dimensional structure of the enzyme and design of inhibitors, which could be used as drugs against TB.

Item Type:	Article
Additional Information:	Copyright of this article belongs to Wiley.
Uncontrolled Keywords:	ASD enzyme, diaminopimelic acid, Mycobacterium tuberculosis H37Rv, tuberculosis.
Subjects:	Q Science > QR Microbiology
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	15 Feb 2012 14:39
Last Modified:	09 Jan 2015 11:16
URI:	http://crdd.osdd.net/open/id/eprint/985

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