BCIpep: A database of B-cell epitopes.

Saha, Sudipto and Bhasin, Manoj and Raghava, G.P.S. (2005) BCIpep: A database of B-cell epitopes. Nucleic acids research. ISSN 1362-4962

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B-cell epitopes are vital in designing peptide-based vaccine, in diseases diagnosis and also for allergy research. This practical importance creates a need for an integrated source of information about them. We developed a databaseBcipep, of experimentally determined B-cell epitopes of antigenic proteins. This is a curated database where detailed information about the epitopes are collected and compiled from published literature and existing databases. It covers a wide range of pathogenic organisms like virus, bacteria, protozoa and fungi. Each entry in database provides full information about a B-cell epitope that includes amino acid sequences, source of the antigenic protein, immunogenicity, model organism and antibody generation/neutralization test. The database have number of web tools and user friendly web interface which allows user to perform various tasks; i) keyword search on any field; ii) mapping of known peptides (B-cell epitope) on a given antigen sequence; iii) BLAST search etc. It also provides links to various databases such as GenBank, PDB, SWISS-PROT and MHCBN for further detailed information about epitopes. The database now contains 2700 entries including 1350 epitopes in the non-redundant datasets

Item Type: Article
Additional Information: OPEN ACCESS
Subjects: Q Science > QR Microbiology > QR180 Immunology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 15 Feb 2012 14:39
Last Modified: 15 Feb 2012 14:39
URI: http://crdd.osdd.net/open/id/eprint/986

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