%A Poonam Rampal
%A H S Saini
%A Mayil Raj
%A Swapandeep Singh Chimni
%A Bhupinder Singh Chadha
%O Copyright of this article belongs to Elsevier Science.
%J Bioresource technology
%T Enantiocomplementary reduction of 3-phenylthiopropan-2-one by Bacillus sp.: effect of medium components.
%X The enantioselectivity of the enzymes responsible for reduction of prochiral compound 3-phenylthiopropan-2-one was dependent on the concentration of yeast extract and glucose in the growth medium. Low concentrations of yeast extract (0.1-0.9% w/v) favored the formation of S-enantiomer (62% ee at 0.1% w/v yeast extract) of 3-phenylthiopropan-2-ol. However, R-enantiomer of the reduced product was formed when MSM was supplemented with yeast extract at a concentration of 1% (w/v) or more with a maximum ee of 85% at 2.0% (w/v) yeast extract supplement in the growth medium.
%N 3
%K Asymmetric reduction; Enantioselectivity; Yeast extract
%P 725-8
%V 98
%D 2007
%I Elsevier Science
%L open1021