title: Role of AbeS, a Novel Efflux Pump of the SMR Family of Transporters, in Resistance to Antimicrobial Agents in Acinetobacter baumannii
creator: Srinivasan, V. B.
creator: Rajamohan, Govindan
creator: Gebreyes, Wondwossen A
subject: QR Microbiology
description: In this study, a chromosomally encoded putative drug efflux pump of the SMR family, named AbeS, from a  multidrug-resistant strain of Acinetobacter baumannii was characterized to elucidate its role in antimicrobial  resistance. Expression of the cloned abeS gene in hypersensitive Escherichia coli host KAM32 resulted in  decreased susceptibility to various classes of antimicrobial agents, detergents, and dyes. Deletion of the abeS  gene in A. baumannii confirmed its role in conferring resistance to these compounds.
publisher: ASM
date: 2009
type: Article
type: PeerReviewed
format: application/pdf
identifier: http://crdd.osdd.net/open/1082/1/rajamohan2009.pdf
relation: http://dx.doi.org/10.1128/AAC.00748-09
identifier:   Srinivasan, V. B. and Rajamohan, Govindan and Gebreyes, Wondwossen A  (2009) Role of AbeS, a Novel Efflux Pump of the SMR Family of Transporters, in Resistance to Antimicrobial Agents in Acinetobacter baumannii.  Antimicrobial Agents and Chemotherapy, 53 (12).  pp. 5312-5316.  ISSN 0066-4804     
relation: http://crdd.osdd.net/open/1082/