creators_name: Srinivasan, V. B.
creators_name: Rajamohan, Govindan
creators_name: Gebreyes, Wondwossen A
type: article
datestamp: 2012-02-28 16:12:26
lastmod: 2015-01-07 06:44:01
metadata_visibility: show
title: Role of AbeS, a Novel Efflux Pump of the SMR Family of Transporters, in Resistance to Antimicrobial Agents in Acinetobacter baumannii
ispublished: pub
subjects: QR
full_text_status: restricted
note: Copyright of this article belongs to ASM.
abstract: In this study, a chromosomally encoded putative drug efflux pump of the SMR family, named AbeS, from a
multidrug-resistant strain of Acinetobacter baumannii was characterized to elucidate its role in antimicrobial
resistance. Expression of the cloned abeS gene in hypersensitive Escherichia coli host KAM32 resulted in
decreased susceptibility to various classes of antimicrobial agents, detergents, and dyes. Deletion of the abeS
gene in A. baumannii confirmed its role in conferring resistance to these compounds.
date: 2009
date_type: published
publication: Antimicrobial Agents and Chemotherapy
volume: 53
number: 12
publisher: ASM
pagerange: 5312-5316
id_number: doi:10.1128/AAC.00748-09
refereed: TRUE
issn: 0066-4804
official_url: http://dx.doi.org/10.1128/AAC.00748-09
related_url_url: http://aac.asm.org/content/53/12/5312.full.pdf+html
related_url_type: pub
citation:   Srinivasan, V. B. and Rajamohan, Govindan and Gebreyes, Wondwossen A  (2009) Role of AbeS, a Novel Efflux Pump of the SMR Family of Transporters, in Resistance to Antimicrobial Agents in Acinetobacter baumannii.  Antimicrobial Agents and Chemotherapy, 53 (12).  pp. 5312-5316.  ISSN 0066-4804     
document_url: http://crdd.osdd.net/open/1082/1/rajamohan2009.pdf