TY - JOUR N1 - Copyright of this article belongs to OUP. ID - open1248 UR - http://jid.oxfordjournals.org/content/206/3/366.full.pdf+html IS - 3 A1 - Mahajan, Sahil A1 - Chandra, Vemika A1 - Dave, Sandeep A1 - Nanduri, Ravikanth A1 - Gupta, Pawan Y1 - 2012/08/01/ N2 - Mycobacterium tuberculosis, the causative agent of tuberculosis, has a remarkable ability to usurp its host's innate immune response, killing millions of infected people annually. One approach to manage infection is prevention through the use of natural agents. In this regard, stem bromelain (SBM), a pharmacologically active member of the sulfhydryl proteolytic enzyme family, obtained from Ananas comosus and possessing a remarkable ability to induce the innate and acquired immune systems, is important. PB - Oxford University Press JF - The Journal of infectious diseases VL - 206 SN - 1537-6613 TI - Stem bromelain-induced macrophage apoptosis and activation curtail Mycobacterium tuberculosis persistence. SP - 366 EP - 76 ER -