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primary topic: CPPsite: a curated database of cell penetrating peptides.

CPPsite: a curated database of cell penetrating peptides.
type: AcademicArticle
type: Article
abstract: Delivering drug molecules into the cell is one of the major challenges in the process of drug development. In past, cell penetrating peptides have been successfully used for delivering a wide variety of therapeutic molecules into various types of cells for the treatment of multiple diseases. These peptides have unique ability to gain access to the interior of almost any type of cell. Due to the huge therapeutic applications of CPPs, we have built a comprehensive database 'CPPsite', of cell penetrating peptides, where information is compiled from the literature and patents. CPPsite is a manually curated database of experimentally validated 843 CPPs. Each entry provides information of a peptide that includes ID, PubMed ID, peptide name, peptide sequence, chirality, origin, nature of peptide, sub-cellular localization, uptake efficiency, uptake mechanism, hydrophobicity, amino acid frequency and composition, etc. A wide range of user-friendly tools have been incorporated in this database like searching, browsing, analyzing, mapping tools. In addition, we have derived various types of information from these peptide sequences that include secondary/tertiary structure, amino acid composition and physicochemical properties of peptides. This database will be very useful for developing models for predicting effective cell penetrating peptides. Database URL: http://crdd.osdd.net/raghava/cppsite/.
date: 2012
volume: 2012
is part of: Database : the journal of biological databases and curation
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: CPPsite: a curated database of cell penetrating peptides. (PDF)
has version: CPPsite: a curated database of cell penetrating peptides. (PDF)
has published: CPPsite: a curated database of cell penetrating peptides. (PDF)
has document: CPPsite: a curated database of cell penetrating peptides. (Other)
subject: QR Microbiology

CPPsite: a curated database of cell penetrating peptides. (PDF)
type: Document
license: http://creativecommons.org/licenses/by-nd/3.0/
has file: raghava2012.2.pdf
has part: raghava2012.2.pdf

Oxford University Press
type: Organization

Database : the journal of biological databases and curation
type: Collection
issn: 17580463

Rahul Kumar
type: Person
given name: Rahul
family name: Kumar

Ankur Gautam
type: Person
given name: Ankur
family name: Gautam

Pallavi Kapoor
type: Person
given name: Pallavi
family name: Kapoor

Harinder Singh
type: Person
given name: Harinder
family name: Singh

Kumardeep Chaudhary
type: Person
given name: Kumardeep
family name: Chaudhary

G.P.S. Raghava
type: Person
given name: G.P.S.
family name: Raghava

Atul Tyagi
type: Person
given name: Atul
family name: Tyagi

CPPsite: a curated database of cell penetrating peptides. (Other)
type: Document
is version of: CPPsite: a curated database of cell penetrating peptides. (PDF)
is volatile version of: CPPsite: a curated database of cell penetrating peptides. (PDF)
is index codes version of: CPPsite: a curated database of cell penetrating peptides. (PDF)
has file: indexcodes.txt
has part: indexcodes.txt

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primary topic: CPPsite: a curated database of cell penetrating peptides.

QR Microbiology
type: Concept