@article{open1545,
          volume = {809},
           month = {January},
          author = {Satish K Tuteja and  Priyanka and Vijayender Bhalla and Akash Deep and A K Paul and C Raman Suri},
           title = {Graphene-gated biochip for the detection of cardiac marker Troponin I.},
       publisher = {    Amsterdam : Elsevier},
         journal = {Analytica chimica acta},
           pages = {148--54},
            year = {2014},
        keywords = {Biochip; Graphene sheets; Lithium ion intercalation; Troponin I},
             url = {http://crdd.osdd.net/open/1545/},
        abstract = {We report lithium ion intercalation mediated efficient exfoliation of graphite to form monolithic graphene sheets which have subsequently been investigated for the development of highly sensitive label-free electrochemical detection platform for cardiac biomarker, Troponin I (cTnI). The spectroscopic and morphological analysis demonstrated the formation of defect free graphene sheets which were successfully employed to fabricate an inter-digited microdevice in a drain-source configuration on a silicon biochip. The graphene gated biochip functionalized with anti-cTnI antibodies used in label free detection of cTnI which exhibited an excellent sensitivity in the picogram range ({\texttt{\char126}}1 pg mL(-1)) for cTnI without the use of any enzymatic amplification that promises its potential applicability for bio-molecular detection in clinical diagnosis.}
}