TY  - JOUR
N1  - Copyright of this article belongs to OUP.
ID  - open1660
UR  - http://gbe.oxfordjournals.org/content/7/3/916/suppl/DC1
IS  - 3
A1  - Agrawal, Yamini
A1  - Khatri, Indu
A1  - Subramanian, Srikrishna
A1  - Shenoy,, Belle Damodara 
Y1  - 2015/03//
N2  - Hirsutella thompsonii (Ht) is a fungal pathogen of acarines and the primary cause of epizootics among mites. The draft genomes of two isolates of Ht (MTCC 3556: Ht3, 34.6 Mb and MTCC 6686: Ht6, 34.7 Mb) are presented and compared with the genomes of Beauveria bassiana (Bb) ARSEF 2860 and Ophiocordyceps sinensis (Os) CO18. Comparative analysis of carbohydrate active enzymes, pathogen-host interaction genes, metabolism-associated genes, and genes involved in biosynthesis of secondary metabolites in the four genomes was carried out. Reduction in gene family sizes in Ht3 and Os as compared with Ht6 and Bb is observed. Analysis of the mating type genes in Ht reveals the presence of MAT idiomorphs which is suggestive of cryptic sexual traits in Ht. We further identify and classify putative chitinases that may function as virulence factors in fungal entomopathogens due to their role in degradation of arthropod cuticle.
PB  - Oxford University Press
JF  - Genome biology and evolution
VL  - 7
KW  - glycoside hydrolase family 18;mycoinsecticide;pathogen?host interactions;phylogenetic classification;subgroups A
KW  -  B
KW  -  and C
SN  - 1759-6653
TI  - Genome sequence, comparative analysis, and evolutionary insights into chitinases of entomopathogenic fungus Hirsutella thompsonii.
SP  - 916
EP  - 30
ER  -