title: Gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-κB, Beclin-1, p62 and NBR1) in human bladder cancer cells. creator: Ishaq, Mohammad creator: Khan, Mohammad Aslam creator: Sharma, Kapil creator: Sharma, Gaurav creator: Dutta, Rajesh Kumar creator: Majumdar, Sekhar subject: QR Microbiology description: Gambogic acid is a potent anticancer agent and has been found effective against various types of cancer cells. The present study was addressed to explore the cytotoxic potential of Gambogic acid and the modulation of autophagy and apoptosis in bladder cancer cells T24 and UMUC3. publisher: Elsevier Publisher date: 2014-12 type: Article type: PeerReviewed relation: http://www.sciencedirect.com/science/article/pii/S0304416514003031 identifier: Ishaq, Mohammad and Khan, Mohammad Aslam and Sharma, Kapil and Sharma, Gaurav and Dutta, Rajesh Kumar and Majumdar, Sekhar (2014) Gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-κB, Beclin-1, p62 and NBR1) in human bladder cancer cells. Biochimica et biophysica acta, 1840 (12). pp. 3374-84. ISSN 0006-3002 relation: http://crdd.osdd.net/open/1676/