TY - JOUR N1 - Open Access ID - open1722 UR - http://nar.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=24174543 IS - Databa A1 - Gautam, Ankur A1 - Chaudhary, Kumardeep A1 - Singh, Sandeep A1 - Joshi, Anshika A1 - Anand, Priya A1 - Tuknait, Abhishek A1 - Mathur, Deepika A1 - Varshney, Grish C A1 - Raghava, G.P.S. Y1 - 2014/01// N2 - Hemolytik (http://crdd.osdd.net/raghava/hemolytik/) is a manually curated database of experimentally determined hemolytic and non-hemolytic peptides. Data were compiled from a large number of published research articles and various databases like Antimicrobial Peptide Database, Collection of Anti-microbial Peptides, Dragon Antimicrobial Peptide Database and Swiss-Prot. The current release of Hemolytik database contains ?3000 entries that include ?2000 unique peptides whose hemolytic activities were evaluated on erythrocytes isolated from as many as 17 different sources. Each entry in Hemolytik provides comprehensive information about a peptide, like its name, sequence, origin, reported function, property such as chirality, types (linear and cyclic), end modifications as well as details pertaining to its hemolytic activity. In addition, tertiary structure of each peptide has been predicted, and secondary structure states have been assigned. To facilitate the scientific community, a user-friendly interface has been developed with various tools for data searching and analysis. We hope, Hemolytik will be useful for researchers working in the field of designing therapeutic peptides. PB - Oxford University Press JF - Nucleic acids research VL - 42 KW - hemolytic and non-hemolytic peptides; database SN - 1362-4962 TI - Hemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides. SP - D444 EP - 9 ER -