creators_name: Gautam, Ankur
creators_name: Chaudhary, Kumardeep
creators_name: Singh, Sandeep
creators_name: Joshi, Anshika
creators_name: Anand, Priya
creators_name: Tuknait, Abhishek
creators_name: Mathur, Deepika
creators_name: Varshney, Grish C
creators_name: Raghava, G.P.S.
type: article
datestamp: 2015-07-19 11:43:12
lastmod: 2015-07-19 11:43:12
metadata_visibility: show
title: Hemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides.
ispublished: pub
subjects: QR
keywords: hemolytic and non-hemolytic peptides; database
note: Open Access
abstract: Hemolytik (http://crdd.osdd.net/raghava/hemolytik/) is a manually curated database of experimentally determined hemolytic and non-hemolytic peptides. Data were compiled from a large number of published research articles and various databases like Antimicrobial Peptide Database, Collection of Anti-microbial Peptides, Dragon Antimicrobial Peptide Database and Swiss-Prot. The current release of Hemolytik database contains ∼3000 entries that include ∼2000 unique peptides whose hemolytic activities were evaluated on erythrocytes isolated from as many as 17 different sources. Each entry in Hemolytik provides comprehensive information about a peptide, like its name, sequence, origin, reported function, property such as chirality, types (linear and cyclic), end modifications as well as details pertaining to its hemolytic activity. In addition, tertiary structure of each peptide has been predicted, and secondary structure states have been assigned. To facilitate the scientific community, a user-friendly interface has been developed with various tools for data searching and analysis. We hope, Hemolytik will be useful for researchers working in the field of designing therapeutic peptides.
date: 2014-01
date_type: published
publication: Nucleic acids research
volume: 42
number: Databa
publisher: Oxford University Press
pagerange: D444-9
refereed: TRUE
issn: 1362-4962
official_url: http://nar.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=24174543
citation:   Gautam, Ankur and Chaudhary, Kumardeep and Singh, Sandeep and Joshi, Anshika and Anand, Priya and Tuknait, Abhishek and Mathur, Deepika and Varshney, Grish C and Raghava, G.P.S.  (2014) Hemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides.  Nucleic acids research, 42 (Databa).  D444-9.  ISSN 1362-4962