@article{open1734,
          volume = {10},
          number = {1},
          author = {Gurmeet Kaur and Srikrishna Subramanian},
            note = {Open Access},
           title = {A novel RING finger in the C-terminal domain of the coatomer protein {\ensuremath{\alpha}}-COP.},
       publisher = {BioMed Central},
            year = {2015},
         journal = {Biology direct},
           pages = {70},
             url = {http://crdd.osdd.net/open/1734/},
        abstract = {The C-terminal domain of {\ensuremath{\alpha}}-COP, an essential subunit of the COPI coatomer complex, is composed of an all {\ensuremath{\alpha}}-helical region and a small {\ensuremath{\beta}}-sheet domain. We show that this {\ensuremath{\beta}}-sheet domain is a Really Interesting New Gene (RING)-like treble clef zinc finger. The zinc-binding residues are substituted by other aminoacids in many homologs including the structurally-characterized proteins from Saccharomyces cerevisiae and Bos taurus. This RING-like domain is possibly related to those of other vesicle membrane-associated complexes, such as CORVET, HOPS and SEA, and likely mediates interactions with Dsl1p and assist in coat oligomerization.}
}