TY  - JOUR
N1  - Open Access
ID  - open1742
UR  - http://nar.oxfordjournals.org/content/44/D1/D1119.long
IS  - D1
A1  - Singh, Sandeep
A1  - Chaudhary, Kumardeep
A1  - Dhanda, Sandeep Kumar
A1  - Bhalla, Sherry
A1  - Usmani, Salman Sadullah
A1  - Gautam, Ankur
A1  - Tuknait, Abhishek
A1  - Agrawal, Piyush
A1  - Mathur, Deepika
A1  - Raghava, G.P.S.
Y1  - 2016/01/04/
N2  - SATPdb (http://crdd.osdd.net/raghava/satpdb/) is a database of structurally annotated therapeutic peptides, curated from 22 public domain peptide databases/datasets including 9 of our own. The current version holds 19192 unique experimentally validated therapeutic peptide sequences having length between 2 and 50 amino acids. It covers peptides having natural, non-natural and modified residues. These peptides were systematically grouped into 10 categories based on their major function or therapeutic property like 1099 anticancer, 10585 antimicrobial, 1642 drug delivery and 1698 antihypertensive peptides. We assigned or annotated structure of these therapeutic peptides using structural databases (Protein Data Bank) and state-of-the-art structure prediction methods like I-TASSER, HHsearch and PEPstrMOD. In addition, SATPdb facilitates users in performing various tasks that include: (i) structure and sequence similarity search, (ii) peptide browsing based on their function and properties, (iii) identification of moonlighting peptides and (iv) searching of peptides having desired structure and therapeutic activities. We hope this database will be useful for researchers working in the field of peptide-based therapeutics.
PB  - Oxford University Press
JF  - Nucleic acids research
VL  - 44
KW  - Therapeutic peptides
SN  - 1362-4962
TI  - SATPdb: a database of structurally annotated therapeutic peptides.
SP  - D1119
EP  - 26
ER  -