%0 Journal Article %@ 1745-6150 %A Kaur, Gurmeet %A Subramanian, Srikrishna %D 2015 %F open:1764 %I BioMed Central %J Biology direct %K Binuclear treble clefs; zinc fingers; B-box; ZZ domain; N-end rule; novel fold; U-box %P 36 %T The UBR-box and its relationship to binuclear RING-like treble clef zinc fingers. %U http://crdd.osdd.net/open/1764/ %V 10 %X The N-end rule pathway is a part of the ubiquitin-dependent proteolytic system wherein N-recognin proteins recognize the amino terminal degradation signals (N-degrons) of the substrate. The type 1 N-degron recognizing UBR-box domain of the eukaryotic Arg/N-end rule pathway is known to possess a novel three-zinc-stabilized heart-shaped fold. %Z Open Access