%0 Journal Article %@ 2044-4753 %A Srivastava, Gautam %A Pal, Mohan %A Kaur, Suneet %A Jolly, R S %D 2015 %F open:1781 %I Royal Society of Chemistry %J Catalysis Science & Technology %K Ketones %N 1 %P 105-108 %T A highly efficient designer cell for enantioselective reduction of ketones %U http://crdd.osdd.net/open/1781/ %V 5 %X A designer cell, surf-crs-gdh, coexpressing carbonyl reductase (crs) and glucose dehydrogenase (gdh) on the cell surface has been constructed and its enzyme activities are compared with those of the corresponding cell, cyto-crs-gdh, coexpressing crs and gdh in cytosol. For various ketones, surf-crs-gdh exhibited 48- to 265-fold higher crs activity per unit protein compared to cyto-crs-gdh. %Z Copyright of this article belongs to RSC.