TY  - JOUR
N1  - Copyright of this article belongs to Elsevier Science
ID  - open1815
UR  - http://dx.doi.org/10.1016/j.biortech.2014.10.105
A1  - Chopra, Lipsy
A1  - Singh, Gurdeep
A1  - Jena, Kautilya Kumar
A1  - Verma, Himanshu
A1  - Sahoo, Debendra K
Y1  - 2015///
N2  - Media composition and environmental conditions were optimized using statistical tools, Plackett Burman design and response surface methodology, to maximize the yield of a bacteriocin, named as sonorensin, from a new marine isolate Bacillus sonorensis MT93 showing broad spectrum of antimicrobial activity. Under optimized conditions, MT93 produced 15-fold higher yield of sonorensin compared to that under initial fermentation conditions. As oxygen supply is a critical parameter controlling growth and product formation in aerobic bioprocesses and used as a parameter for bioprocess scale up, the effects of oxygen transfer, in terms of volumetric oxygen transfer coefficient (kLa), on production of sonorensin was investigated using optimized medium composition in a bioreactor. Studies on effectiveness of sonorensin against Staphylococcus aureus and Listeria monocytogenes in fruit juice and as a preservative in pasteurized milk demonstrated its potential as a biopreservative in fruit products and shelf life extender of the pasteurized milk.
PB  - Elsevier Science
JF  - Bioresource Technology
VL  - 175
KW  - Bacillus sonorensis; Sonorensin; Optimization; Volumetric oxygen transfer coefficient; Biopreservative
SN  - 09608524
TI  - Bioprocess development for the production of sonorensin by Bacillus sonorensis MT93 and its application as a food preservative
SP  - 358
EP  - 366
ER  -