creators_name: Singh, Harinder
creators_name: Kumar, Rahul
creators_name: Singh, Sandeep
creators_name: Chaudhary, Kumardeep
creators_name: Gautam, Ankur
creators_name: Raghava, G.P.S.
type: article
datestamp: 2016-09-29 06:17:38
lastmod: 2016-09-29 06:17:38
metadata_visibility: show
title: Prediction of anticancer molecules using hybrid model developed on molecules screened against NCI-60 cancer cell lines.
ispublished: pub
subjects: QR
keywords: Bioinformatics, cancer
note: Open Access
abstract: In past, numerous quantitative structure-activity relationship (QSAR) based models have been developed for predicting anticancer activity for a specific class of molecules against different cancer drug targets. In contrast, limited attempt have been made to predict the anticancer activity of a diverse class of chemicals against a wide variety of cancer cell lines. In this study, we described a hybrid method developed on thousands of anticancer and non-anticancer molecules tested against National Cancer Institute (NCI) 60 cancer cell lines.
date: 2015
date_type: published
publication: BMC cancer
volume: 16
number: 1
publisher: BIOMED CENTRAL
pagerange: 77
refereed: TRUE
issn: 1471-2407
official_url: http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2082-y
citation:   Singh, Harinder and Kumar, Rahul and Singh, Sandeep and Chaudhary, Kumardeep and Gautam, Ankur and Raghava, G.P.S.  (2015) Prediction of anticancer molecules using hybrid model developed on molecules screened against NCI-60 cancer cell lines.  BMC cancer, 16 (1).  p. 77.  ISSN 1471-2407     
document_url: http://crdd.osdd.net/open/1833/1/87.pdf