%0 Journal Article %@ 1471-2105 %A Acharya, Giriraj %A Kaur, Gurmeet %A Subramanian, Srikrishna %D 2016 %F open:1850 %I BioMed Central %J BMC bioinformatics %K Barrel packing; Heme; Hemoprotein; Iron metabolism; Protein evolution %P 168 %T Evolutionary relationships between heme-binding ferredoxin α + β barrels. %U http://crdd.osdd.net/open/1850/ %V 17 %X The α + β barrel superfamily of the ferredoxin-like fold consists of a functionally diverse group of evolutionarily related proteins. The barrel architecture of these proteins is formed by either homo-/hetero-dimerization or duplication and fusion of ferredoxin-like domains. Several members of this superfamily bind heme in order to carry out their functions. %Z Open Access