%A Giriraj Acharya %A Gurmeet Kaur %A Srikrishna Subramanian %O Open Access %J BMC bioinformatics %T Evolutionary relationships between heme-binding ferredoxin ? + ? barrels. %X The ? + ? barrel superfamily of the ferredoxin-like fold consists of a functionally diverse group of evolutionarily related proteins. The barrel architecture of these proteins is formed by either homo-/hetero-dimerization or duplication and fusion of ferredoxin-like domains. Several members of this superfamily bind heme in order to carry out their functions. %K Barrel packing; Heme; Hemoprotein; Iron metabolism; Protein evolution %P 168 %V 17 %D 2016 %I BioMed Central %L open1850