TY  - JOUR
ID  - open2091
UR  - http://crdd.osdd.net/open/2091/
A1  - Muthukumarappa, Thungapathra
A1  - Ghosh, Amit
A1  - Sharma, Charu
A1  - Gupta, Naveen
A1  - Mukhopadhyay, Ashish
A1  - Hemanta, Kole
A1  - Nair, Gopinath
A1  - Ghosh, Balakrish
A1  - Kumar, Ranajit
TI  - rocess for the isolation of a nontoxinogenic vibrio cholerae strain and a process for preparing cholera vaccine from said vibrio cholerae strain
Y1  - 2000///
N2  - A process for the isolation of nontoxinogenic V. cholerae strain and a process for preparing a cholera vaccine from said V. cholerae strain, said process comprising (a) isolating V. cholerae from the stool of a patient suffering from cholera by spreading the stool on a selector medium specific for V. cholerae, (b) separating the non-toxinogenic V. cholerae strain from the population of the V. cholerae strains isolated in step (a), and (c) incorporating immunogenic cholera toxin (ctx) B subunit gene into the chromosome of the strain by conventional methods to produce the vaccine.
ER  -