TY - JOUR N1 - Open Access ID - open2120 UR - https://gutpathogens.biomedcentral.com/articles/10.1186/s13099-016-0153-x A1 - Sengupta, Chirantana A1 - Ekka, Manjula A1 - Arora, Saurabh A1 - Dhaware, Prashant D A1 - Chowdhury, Rukhsana A1 - Raychaudhuri, Saumya Y1 - 2017/// N2 - converts glucose into either acid or the neutral end product acetoin and its survival in carbohydrate enriched media is linked to the nature of the byproducts produced. It has been demonstrated in this study that strain isolated from the gut of healthy human volunteers and the commonly used probiotic Nissle strain that metabolize glucose to acidic byproducts drastically reduce the survival of strains irrespective of their glucose sensitivity and acetoin production status. Accordingly, glucose transport mutants that produce lower amounts of acidic metabolites had little effect on the survival of in cocultures. Thus, cross feeding of byproducts of glucose metabolism by heterologous bacteria modulates the survival of in glucose rich medium suggesting that composition of the gut microbiota could influence the outcome of infection especially when glucose based ORS is administered. PB - BMC ( Part of Springer Nature) JF - Gut pathogens VL - 9 KW - Cocultures; E. coli Nissle 1917; E. coli glucose transport mutants; V. cholerae survival SN - 1757-4749 TI - Cross feeding of glucose metabolism byproducts of human gut isolates and probiotic strains affect survival of Vibrio cholerae. ER -