%A Chirantana Sengupta
%A Manjula Ekka
%A Saurabh Arora
%A Prashant D Dhaware
%A Rukhsana Chowdhury
%A Saumya Raychaudhuri
%O Open Access
%J Gut pathogens
%T Cross feeding of glucose metabolism byproducts of  human gut isolates and probiotic strains affect survival of Vibrio cholerae.
%X  converts glucose into either acid or the neutral end product acetoin and its survival in carbohydrate enriched media is linked to the nature of the byproducts produced. It has been demonstrated in this study that  strain isolated from the gut of healthy human volunteers and the commonly used probiotic  Nissle strain that metabolize glucose to acidic byproducts drastically reduce the survival of  strains irrespective of their glucose sensitivity and acetoin production status. Accordingly,  glucose transport mutants that produce lower amounts of acidic metabolites had little effect on the survival of  in cocultures. Thus, cross feeding of byproducts of glucose metabolism by heterologous bacteria modulates the survival of  in glucose rich medium suggesting that composition of the gut microbiota could influence the outcome of  infection especially when glucose based ORS is administered.
%K Cocultures; E. coli Nissle 1917; E. coli glucose transport mutants; V. cholerae survival
%P 3
%V 9
%D 2017
%I BMC ( Part of Springer Nature)
%L open2120