creators_name: Choudhary, Pravinkumar
creators_name: Nagar, Rupa
creators_name: Singh, Vaidhvi
creators_name: Bhat, Aadil Hussain
creators_name: Sharma, Yogita
creators_name: Rao, Alka
type: article
datestamp: 2019-03-18 16:11:02
lastmod: 2019-03-18 16:11:02
metadata_visibility: show
title: ProGlycProt V2.0, a repository of experimentally validated glycoproteins and protein glycosyltransferases of prokaryotes.
ispublished: pub
subjects: QR
keywords: protein glycosylation; prokaryotic glycoproteins; glycosyltransferase; bacteria, archaea
abstract: Knowledge of glycosylation status and glycan-pattern of proteins are of considerable medical, academic and application interest. ProGlycProt V2.0 (www.proglycprot.org) therefore, is conceived and maintained as an exclusive web-resource providing comprehensive information on experimentally validated glycoproteins and protein glycosyltransferases (GTs) of prokaryotic origin. The second release of ProGlycProt V2.0 features a major update with a 191 % increase in the total number of entries, manually collected and curated from 607 peer-reviewed publications on the subject. Protein GTs from prokaryotes that catalyze a varied range of glycan linkages are amenable glycoengineering tools. Therefore, the second release presents content that is greatly expanded and reorganized in two sub-databases: ProGPdb and ProGTdb. While ProGPdb provides information about validated glycoproteins (222 entries), ProGTdb catalogs enzymes/proteins that are instrumental in protein glycosylation, directly (122) or as accessory proteins (182). ProGlycProt V2.0 remains highly cross-referenced yet exclusive and complementary in content to other related databases. The second release further features enhanced search capability, a "compare" entries option and an innovative geoanalytical tool (MapView) facilitating location-assisted search-cum filtering of the entries using geo-positioning information of researchers/groups cited in the ProGlycProt V2.0 databases. Thus, ProGlycProt V2.0 continues to serve as a useful one-point web-resource on various evidence-based information on protein glycosylation in prokaryotes.
date: 2019-03-05
date_type: published
publication: Glycobiology
publisher: Oxford University Press
refereed: TRUE
issn: 1460-2423
official_url: https://academic.oup.com/glycob/advance-article/doi/10.1093/glycob/cwz013/5369880
citation:   Choudhary, Pravinkumar and Nagar, Rupa and Singh, Vaidhvi and Bhat, Aadil Hussain and Sharma, Yogita and Rao, Alka  (2019) ProGlycProt V2.0, a repository of experimentally validated glycoproteins and protein glycosyltransferases of prokaryotes.  Glycobiology.   ISSN 1460-2423